Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12446302 | 0.84 | GPR3 (0.56) | GPR3KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL4696033 | 0.79 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL36332 | 0.79 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL29374932 | 0.79 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL9160474 | 0.79 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL10476774 | 0.79 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1RAB9A | |
| SCHEMBL30515127 | 0.79 | GPR3 (0.68) | GPR3KDM4EMAPTALDH1A1RAB9A | |
| Hydrogen Sulfide SCHEMBL23748456 | 0.77 | GPR3 (0.65) | GPR3KDM4EMAPTALDH1A1RAB9A | |
| Ammonia Solution, Strong SCHEMBL6303550 | 0.77 | GPR3 (0.65) | GPR3KDM4EMAPTALDH1A1RAB9A | |
| Ammonia Solution, Strong SCHEMBL1871981 | 0.77 | GPR3 (0.65) | GPR3KDM4EMAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062386-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE (US) | 2026-03-05 | — | — | US | disclosed |
| US-12509428-B2 | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| CN-112449635-B | Polymerizable fused tricyclic compounds as UV and visible light absorbers | 强生视力健公司 | 2024-10-29 | — | — | CN | disclosed |
| US-20230117655-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2023-04-20 | — | — | US | disclosed |
| US-20230117655-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2023-04-20 | — | — | US | disclosed |
| EP-3990431-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | Johnson & Johnson Vision Care, Inc. (US) | 2022-05-04 | — | — | EP | disclosed |
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2020-12-31 | — | — | US | disclosed |
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2020-12-31 | — | — | US | disclosed |
| WO-2020261021-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020261021-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | ERCC4, ERCC1, F12 | GPR3 2132/4885KDM4E 2856/4885MAPT 244/4885 |
| US-20260062386-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | ERCC1, MCM6, GPR6 | GPR3 130/4885KDM4E 3698/4885MAPT 3087/4885 |
| US-12509428-B2 | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | ERCC1, OGG1, ERCC4 | GPR3 136/4885KDM4E 701/4885MAPT 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.