Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184117 | 1.00 | P2RX4 (0.54) | P2RX4POLBGLAALDH1A1LMNA | |
| SCHEMBL3557234 | 0.91 | POLB (0.64) | P2RX4POLBGLAALDH1A1LMNA | |
| SCHEMBL11873935 | 0.85 | P2RX4 (0.71) | P2RX4POLBGLAALDH1A1LMNA | |
| SCHEMBL12216219 | 0.81 | POLB (0.80) | P2RX4POLBGLAALDH1A1LMNA | |
| SCHEMBL28509508 | 0.76 | POLB (0.46) | POLBGLAALDH1A1LMNAKDM4E | |
| SCHEMBL29395135 | 0.76 | POLB (0.46) | POLBGLAALDH1A1LMNAKDM4E | |
| SCHEMBL23318256 | 0.76 | PTGER4 (0.50) | POLBALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL2424796 | 0.75 | P2RX4 (0.69) | P2RX4POLBGLAALDH1A1LMNA | |
| Methacrylic Acid SCHEMBL28000391 | 0.72 | HPGD (0.44) | P2RX4POLBGLAALDH1A1LMNA | |
| SCHEMBL28505644 | 0.72 | LMNA (0.47) | POLBGLAALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509428-B2 | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2025-12-30 | — | — | US | disclosed |
| US-20230117655-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2023-04-20 | — | — | US | disclosed |
| EP-3990431-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | Johnson & Johnson Vision Care, Inc. (US) | 2022-05-04 | — | — | EP | disclosed |
| CN-112449635-A | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | 强生视力健公司 | 2021-03-05 | — | — | CN | disclosed |
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. | 2020-12-31 | — | — | US | disclosed |
| WO-2020261021-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407324-A1 | POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT | ERCC4, ERCC1, F12 | P2RX4 1295/4885POLB 942/4885GLA 827/4885 |
| US-12509428-B2 | Polymerizable fused tricyclic compounds as absorbers of UV and visible light | ERCC1, OGG1, ERCC4 | P2RX4 384/4885POLB 2513/4885GLA 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.