Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395135 | 1.00 | POLB (0.46) | POLBAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL31425730 | 0.86 | MAP2 (0.45) | GAAPADI4 | |
| SCHEMBL31425731 | 0.86 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL28981318 | 0.85 | MAP2 (0.50) | POLBALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL28981320 | 0.85 | ALDH1A1 (0.45) | POLBALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29099041 | 0.84 | ALDH1A1 (0.45) | POLBAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL29398362 | 0.81 | MAPT (0.36) | AGTR1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL2490336 | 0.80 | AGTR1 (0.53) | POLBAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL29099037 | 0.80 | AGTR1 (0.42) | POLBAGTR1ALDH1A1KDM4EHPGD | |
| SCHEMBL3557234 | 0.80 | POLB (0.64) | POLBALDH1A1KDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773334-A | Indolo [2, 1-alpha ] isoquinoline compound and preparation method and application thereof | 杭州医学院 | 2022-07-22 | — | — | CN | claimed |
| CN-113698399-B | Isoquinoline compound and preparation method and application thereof | 浙江省人民医院 | 2022-05-27 | — | — | CN | claimed |
| CN-113698399-A | Isoquinoline compound and preparation method and application thereof | 浙江省人民医院 | 2021-11-26 | — | — | CN | claimed |
| CN-119372671-A | Method for synthesizing amino acid compound by participation of carbon dioxide | 新疆大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-114773334-B | Indolo [2, 1-alpha ] isoquinoline compound and preparation method and application thereof | 杭州医学院 | 2023-09-19 | — | — | CN | disclosed |
| CN-114105981-B | Method for preparing benzimidazole [2,1-a ] isoquinoline-6 (5H) -ketone compound | 怀化学院 | 2022-12-30 | — | — | CN | disclosed |
| CN-114773334-A | Indolo [2, 1-alpha ] isoquinoline compound and preparation method and application thereof | 杭州医学院 | 2022-07-22 | — | — | CN | disclosed |
| CN-113698399-B | Isoquinoline compound and preparation method and application thereof | 浙江省人民医院 | 2022-05-27 | — | — | CN | disclosed |
| CN-114105981-A | Method for preparing benzimidazole [2,1-a ] isoquinoline-6 (5H) -ketone compound | 怀化学院 | 2022-03-01 | — | — | CN | disclosed |
| CN-110467640-B | Preparation method of indole or benzimidazole-isoquinolone condensed heterocyclic derivative | 南昌航空大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-113698399-A | Isoquinoline compound and preparation method and application thereof | 浙江省人民医院 | 2021-11-26 | — | — | CN | disclosed |
| CN-112174957-B | Method for synthesizing 5-selenoindolo [2,1-a ] isoquinoline-6 (5H) -ketone compound | 桂林医学院 | 2021-07-02 | — | — | CN | disclosed |
| CN-112174957-A | Method for synthesizing 5-selenoindolo [2,1-a ] isoquinoline-6 (5H) -ketone compound | 桂林医学院 | 2021-01-05 | — | — | CN | disclosed |