Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2283181 | 0.83 | PIM1 (0.32) | PIM1PIM2 | |
| SCHEMBL15635289 | 0.57 | HTT (0.58) | — | |
| SCHEMBL29889802 | 0.57 | PDE2A (0.46) | — | |
| SCHEMBL15639465 | 0.56 | ALDH1A1 (0.62) | — | |
| SCHEMBL5322520 | 0.56 | IDH1 (0.35) | — | |
| SCHEMBL30641338 | 0.56 | MAT2A (0.38) | — | |
| SCHEMBL26674794 | 0.56 | MAT2A (0.38) | — | |
| SCHEMBL495687 | 0.55 | DHODH (0.54) | — | |
| SCHEMBL22117225 | 0.55 | BACE1 (0.40) | — | |
| SCHEMBL113996 | 0.55 | DHODH (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110201496-A1 | Substituted 5-Hetaryl-4-Aminopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2011-08-18 | — | — | US | disclosed |
| EP-2001298-A2 | SUBSTITUTED 5-HETARYL-4-AMINOPYRIMIDINES | BASF SE (DE) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007110418-A2 | SUBSTITUTED 5-HETARYL-4-AMINOPYRIMIDINES | BASF SE (DE) | 2007-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201496-A1 | Substituted 5-Hetaryl-4-Aminopyrimidines | CBR3, CBR1, CYC1 | PIM1 4234/4885PIM2 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.