Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2459173 | 0.84 | CYP11B2 (0.48) | PDE2APDE10ACYP11B2DHODHMAPT | |
| SCHEMBL29889826 | 0.84 | CYP11B2 (0.48) | PDE2APDE10ACYP11B2DHODHMAPT | |
| SCHEMBL14715801 | 0.79 | KDM4E (0.47) | MAPTCYP2C19 | |
| SCHEMBL13750510 | 0.78 | DHODH (0.46) | PDE10ACYP11B2DHODHMAPTCYP11B1 | |
| SCHEMBL12947927 | 0.77 | DHODH (0.48) | PDE2APDE10ACYP11B2DHODHMAPT | |
| SCHEMBL26951542 | 0.76 | MAOA (0.46) | PDE2APDE10ACYP11B2DHODHMAPT | |
| SCHEMBL10730124 | 0.75 | ADORA2A (0.49) | DHODHMAPTBACE1NPC1 | |
| SCHEMBL31051044 | 0.74 | DHODH (0.50) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL3876408 | 0.74 | DHODH (0.50) | CYP11B2DHODHMAPTCYP11B1MAOA | |
| SCHEMBL3881160 | 0.72 | CYP11B2 (0.50) | CYP11B2DHODHMAPTCYP11B1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262803-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | Chungdu Anticancer Bioscience Ltd (CN) | 2024-08-08 | — | — | US | disclosed |
| WO-2022199654-A1 | HETEROARYL-HETEROARYL-O-PHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING CANCER DISORDERS | Chengdu Anticancer Bioscience, Ltd. (CN) | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262803-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING DISORDERS | CYP27A1, PNLIP, GOT2 | PDE2A 1580/4885PDE10A 1091/4885CYP11B2 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.