Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274043 | 0.82 | LIPG (0.50) | LIPGLPLROCK1EP300CA1 | |
| SCHEMBL12374507 | 0.79 | MAPK14 (0.45) | LIPGLPLEP300 | |
| SCHEMBL2283066 | 0.77 | P4HB (0.44) | LIPGLPLHIF1A | |
| SCHEMBL2283534 | 0.72 | LIPG (0.43) | LIPGLPLHIF1AROCK1CYP3A4 | |
| SCHEMBL2283537 | 0.72 | LIPG (0.43) | LIPGLPLHIF1AROCK1CYP3A4 | |
| SCHEMBL2145222 | 0.71 | LIPG (0.58) | LIPGLPLCA1CA2CA9 | |
| SCHEMBL2282683 | 0.71 | MAPK14 (0.45) | LIPGLPLHIF1ACA1 | |
| SCHEMBL2282699 | 0.71 | MAPK14 (0.45) | LIPGLPLHIF1ACA1 | |
| SCHEMBL2280542 | 0.70 | MAPK14 (0.47) | LIPGLPLHIF1ACYP3A4ALDH1A1 | |
| SCHEMBL2280780 | 0.70 | LIPG (0.39) | LIPGLPLHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003695-B2 | IKK-beta serine-threonine protein kinase inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2011-08-23 | — | — | US | disclosed |