SCHEMBL22837901

SCHEMBL22837901

Nc1ccccc1/C=C/S(=O)(=O)NC[C@H]1OCC(n2cnc3c(N)ncnc32)[C@@H]1O

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ AHCY P23526 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20711215 0.85 DPP4 (0.58) —
SCHEMBL20711308 0.84 POLB (0.49) —
SCHEMBL20711329 0.81 ADORA3 (0.52) —
SCHEMBL22837883 0.80 ADORA3 (0.37) —
SCHEMBL20711304 0.79 BCHE (0.44) —
SCHEMBL22837892 0.78 TRPM2 (0.58) —
SCHEMBL20711233 0.78 TRPM2 (0.58) —
SCHEMBL12379181 0.78 TRPM2 (0.58) —
SCHEMBL22837893 0.78 TRPM2 (0.58) —
SCHEMBL20711221 0.77 DPP4 (0.56) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10874686-B2 Anthranilyl-adenosinemonosulfamate analogs and uses thereof MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2020-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10874686-B2 Anthranilyl-adenosinemonosulfamate analogs and uses thereof ATIC, SLC35B2, ADORA1 AHCY 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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