SCHEMBL22837935

SCHEMBL22837935

Nc1cccc(F)c1C(=O)NS(=O)(=O)NC[C@H]1OC[C@](O)(n2cnc3c(N)ncnc32)[C@@H]1O

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRPM2 O94759 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22837903 0.87 TRPM2 (0.46) TRPM2
SCHEMBL22837886 0.82 — —
SCHEMBL22837884 0.80 GMPS (0.34) —
SCHEMBL22837936 0.80 PDE4A (0.37) TRPM2
SCHEMBL20711284 0.79 TRPM2 (0.56) TRPM2
SCHEMBL22837883 0.79 ADORA3 (0.37) —
SCHEMBL22837900 0.78 ADORA3 (0.36) —
SCHEMBL21311195 0.77 EGFR (0.44) —
SCHEMBL22837885 0.77 TRPM2 (0.36) TRPM2
SCHEMBL20711180 0.76 TRPM2 (0.56) TRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10874686-B2 Anthranilyl-adenosinemonosulfamate analogs and uses thereof MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2020-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10874686-B2 Anthranilyl-adenosinemonosulfamate analogs and uses thereof ATIC, SLC35B2, ADORA1 TRPM2 2028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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