Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL737722 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL29409289 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL10936850 | 0.77 | TSHR (0.55) | POLBALDH1A1CYP3A4LMNATSHR | |
| Hydrochloric Acid SCHEMBL3973012 | 0.76 | MAPT (0.92) | MAPTMEN1KMT2APOLBTDP1 | |
| Hydrochloric Acid SCHEMBL3973011 | 0.76 | MAPT (0.92) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL8601406 | 0.74 | MAPT (0.88) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL5952772 | 0.73 | TDP1 (0.79) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL27864753 | 0.73 | TDP1 (0.79) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL3178960 | 0.73 | MAPT (0.85) | MAPTMEN1KMT2APOLBTDP1 | |
| SCHEMBL9649469 | 0.73 | TDP1 (0.85) | MAPTMEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041666-A | Acetylating biphenyl, oximating, double Beckmann rearrangement, nitrating, hydrolysis, and reducing | HOECHST CELANESE CORPORATION (US) | 1991-08-20 | — | — | US | claimed |
| US-7999112-B2 | Reusable transition metal complex catalyst useful for the preparation of high pure quality 3,3′-diaminobenzidine and its analogues and a process thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2011-08-16 | — | — | US | disclosed |
| EP-1730102-B1 | A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL | COUNCIL SCIENT IND RES (IN) | 2010-09-22 | — | — | EP | disclosed |
| US-20090131678-A1 | Novel reusable transition metal complex catalyst useful for the preparation of high pure quality 3,3'-diaminobenzidine and its analogues and a process thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2009-05-21 | — | — | US | disclosed |
| EP-1727781-B1 | PROCESS FOR THE PREPARATION OF HIGH QUALITY 3,3',4,4'-TETRAMINOBIPHENYL | COUNCIL SCIENT IND RES (IN) | 2009-05-06 | — | — | EP | disclosed |
| EP-1730102-A1 | A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3 , 4,4'-TETRAMINOBIPHENYL | Council of Scientific and Industrial Research (IN) | 2006-12-13 | — | — | EP | disclosed |
| US-6979749-B2 | Catalytic process for the production of 3,3′, 4,4′-tetraminobiphenyl | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-12-27 | — | — | US | disclosed |
| WO-2005092839-A1 | A NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-10-06 | — | — | WO | disclosed |
| US-20050215823-A1 | NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-09-29 | — | — | US | disclosed |
| US-5041666-A | Acetylating biphenyl, oximating, double Beckmann rearrangement, nitrating, hydrolysis, and reducing | HOECHST CELANESE CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| US-5041666-A | Acetylating biphenyl, oximating, double Beckmann rearrangement, nitrating, hydrolysis, and reducing | HOECHST CELANESE CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215823-A1 | NOVEL CATALYTIC PROCESS FOR THE PRODUCTION OF 3,3', 4,4'-TETRAMINOBIPHENYL | NNMT, CBR3, POR | MAPT 4350/4885MEN1 2108/4885KMT2A 130/4885 |
| US-20090131678-A1 | Novel reusable transition metal complex catalyst useful for the preparation of high pure quality 3,3'-diaminobenzidine and its analogues and a process thereof | CYBB, DDT, NOX4 | MAPT 3729/4885MEN1 2279/4885KMT2A 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.