Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24059784 | 0.90 | — | — | |
| SCHEMBL18051888 | 0.81 | PIM1 (0.39) | — | |
| SCHEMBL18629226 | 0.81 | DCK (0.31) | — | |
| SCHEMBL21014903 | 0.72 | NPC1 (0.31) | — | |
| SCHEMBL10304064 | 0.69 | PTPN11 (0.42) | — | |
| SCHEMBL18902127 | 0.67 | JAK2 (0.35) | — | |
| SCHEMBL19937783 | 0.67 | ALDH1A1 (0.38) | — | |
| SCHEMBL18629001 | 0.65 | PDK1 (0.38) | — | |
| SCHEMBL24059785 | 0.64 | — | — | |
| SCHEMBL21014901 | 0.64 | JAK2 (0.50) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10874673-B2 | Inhibitors of influenza viruses replication | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2020-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10874673-B2 | Inhibitors of influenza viruses replication | ACE, IRF3, ACE2 | CYP2C9 1426/4885PKMYT1 2975/4885MAP3K14 1718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.