Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.40 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839974 | 0.93 | ADRB2 (0.40) | ADRB2CHRM3DRD2DRD4 | |
| SCHEMBL22839902 | 0.89 | ADRB2 (0.37) | ADRB2CHRM3ACHEBCHEBACE1 | |
| SCHEMBL19784370 | 0.83 | ADRB2 (0.50) | ADRB2CHRM3 | |
| SCHEMBL22839980 | 0.83 | ADRB2 (0.56) | ADRB2CHRM3 | |
| SCHEMBL22839981 | 0.82 | ADRB2 (0.46) | ADRB2CHRM3DRD2DRD4 | |
| SCHEMBL22839907 | 0.81 | ADRB2 (0.45) | ADRB2CHRM3DRD2DRD4 | |
| SCHEMBL22839921 | 0.81 | ADRB2 (0.60) | ADRB2CHRM3 | |
| SCHEMBL19784099 | 0.79 | ADRB2 (0.42) | ADRB2CHRM3 | |
| SCHEMBL22839800 | 0.79 | ADRB2 (0.49) | ADRB2CHRM3 | |
| SCHEMBL22839971 | 0.79 | ADRB2 (0.49) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |
| WO-2018011090-A1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-01-18 | — | — | WO | disclosed |