Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 16/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839921 | 0.92 | ADRB2 (0.60) | ADRB2CHRM3CHRM4 | |
| SCHEMBL22839873 | 0.85 | ADRB2 (0.56) | ADRB2CHRM3CHRM4 | |
| SCHEMBL22839974 | 0.84 | ADRB2 (0.40) | ADRB2CHRM3 | |
| SCHEMBL19784600 | 0.83 | ADRB2 (0.40) | ADRB2CHRM3 | |
| SCHEMBL24404548 | 0.83 | ADRB2 (0.52) | ADRB2CHRM3 | |
| SCHEMBL22839800 | 0.83 | ADRB2 (0.49) | ADRB2CHRM3 | |
| SCHEMBL22839971 | 0.83 | ADRB2 (0.49) | ADRB2CHRM3 | |
| SCHEMBL22839981 | 0.83 | ADRB2 (0.46) | ADRB2CHRM3 | |
| SCHEMBL22839872 | 0.82 | ADRB2 (0.70) | ADRB2CHRM3 | |
| SCHEMBL22839907 | 0.82 | ADRB2 (0.45) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011090-A1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-01-18 | — | — | WO | disclosed |