Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.64 |
| ▸ | TLR2 | O60603 | 1/20 | 0.61 |
| ▸ | GLP1R | P43220 | 8/20 | 0.60 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.58 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.56 |
| ▸ | NMT2 | O60551 | 1/20 | 0.56 |
| ▸ | NMT1 | P30419 | 1/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.54 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15720863 | 1.00 | SIRT6 (0.64) | SIRT6SIRT1TLR2GLP1RNOD1 | |
| SCHEMBL15720613 | 1.00 | SIRT6 (0.64) | SIRT6SIRT1TLR2GLP1RNOD1 | |
| SCHEMBL2339540 | 1.00 | SIRT6 (0.64) | SIRT6SIRT1TLR2GLP1RNOD1 | |
| SCHEMBL20542965 | 0.92 | SIRT6 (0.76) | SIRT6SIRT1TLR2GLP1RLPAR3 | |
| SCHEMBL20543083 | 0.92 | SIRT6 (0.76) | SIRT6SIRT1TLR2GLP1RLPAR3 | |
| SCHEMBL23519401 | 0.92 | SIRT6 (0.76) | SIRT6SIRT1TLR2GLP1RLPAR3 | |
| SCHEMBL20542884 | 0.92 | SIRT6 (0.76) | SIRT6SIRT1TLR2GLP1RLPAR3 | |
| SCHEMBL20542968 | 0.92 | SIRT6 (0.76) | SIRT6SIRT1TLR2GLP1RLPAR3 | |
| SCHEMBL20542815 | 0.92 | SIRT6 (0.76) | SIRT6SIRT1TLR2GLP1RLPAR3 | |
| SCHEMBL20829866 | 0.92 | SIRT6 (0.76) | SIRT6SIRT1TLR2GLP1RLPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348396-A1 | Injectable solution at pH7 comprising at least one basal insulin the pI of which is from 5.8 to 8.5, a prandial insulin and/or a gastrointestinal hormone, and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals | ADOCIA (FR) | 2017-12-07 | — | — | US | disclosed |
| US-20170348423-A1 | Injectable solution at pH 7 comprising at least one basal insulin the pl of which is from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals | ADOCIA (FR) | 2017-12-07 | — | — | US | disclosed |
| US-9115218-B2 | Anionic polysaccharides functionalized by at least two hydrophobic groups carried by an at least trivalent spacer | ADOCIA (FR) | 2015-08-25 | — | — | US | disclosed |
| US-20110195913-A1 | Anionic polysaccharides functionalized by at least two hydrophobic groups carried by an at least trivalent spacer | ADOCIA (FR) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348423-A1 | Injectable solution at pH 7 comprising at least one basal insulin the pl of which is from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals | IAPP, IDE, INSR | SIRT6 3384/4885SIRT1 4244/4885TLR2 4592/4885 |
| US-20110195913-A1 | Anionic polysaccharides functionalized by at least two hydrophobic groups carried by an at least trivalent spacer | CD44, CSGALNACT1, ALG1 | SIRT6 3314/4885SIRT1 2516/4885TLR2 46/4885 |
| US-20170348396-A1 | Injectable solution at pH7 comprising at least one basal insulin the pI of which is from 5.8 to 8.5, a prandial insulin and/or a gastrointestinal hormone, and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals | IAPP, F7, GIPR | SIRT6 2765/4885SIRT1 3926/4885TLR2 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.