Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 5/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257728 | 0.90 | NMT1 (0.39) | HRH1 | |
| SCHEMBL22238251 | 0.85 | EPHX2 (0.35) | PTGS1PTGS2 | |
| SCHEMBL17722905 | 0.84 | PTGS1 (0.49) | CASP1BACE1PLA2G10PTGS1PTGS2 | |
| SCHEMBL21153657 | 0.83 | EPHX2 (0.42) | PTGS1PTGS2 | |
| SCHEMBL26083211 | 0.82 | CASP1 (0.35) | CASP1HRH1 | |
| SCHEMBL24860469 | 0.81 | C3AR1 (0.36) | — | |
| SCHEMBL21013511 | 0.80 | CASP1 (0.35) | CASP1CASP3 | |
| SCHEMBL22267887 | 0.78 | CASP1 (0.33) | CASP1 | |
| SCHEMBL23583708 | 0.77 | MEN1 (0.45) | BACE1PTGS1PTGS2 | |
| SCHEMBL18909078 | 0.77 | PTGS1 (0.49) | CASP1PLA2G10PTGS1PTGS2PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626273-B1 | ANTI-CMET ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE | ABBVIE BIOTHERAPEUTICS INC (US) | 2020-12-30 | — | — | EP | disclosed |