Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | SDCBP | O00560 | 4/20 | 0.38 |
| ▸ | SDC2 | P34741 | 4/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22238251 | 0.91 | EPHX2 (0.35) | EPHX2FNTAFNTBMEN1KMT2A | |
| SCHEMBL21727091 | 0.88 | FAAH (0.43) | MEN1KMT2APTGS1PTGS2 | |
| SCHEMBL23583708 | 0.87 | MEN1 (0.45) | EPHX2MEN1KMT2ANPSR1PTGS1 | |
| SCHEMBL26083211 | 0.86 | CASP1 (0.35) | EPHX2 | |
| SCHEMBL22841014 | 0.83 | CASP1 (0.36) | PTGS1PTGS2 | |
| SCHEMBL24860469 | 0.81 | C3AR1 (0.36) | EPHX2FNTAFNTBMEN1KMT2A | |
| SCHEMBL19514146 | 0.80 | PTGS1 (0.55) | EPHX2FNTAFNTBSDCBPSDC2 | |
| SCHEMBL15189321 | 0.80 | PTGS1 (0.55) | EPHX2FNTAFNTBSDCBPSDC2 | |
| SCHEMBL19257728 | 0.80 | NMT1 (0.39) | — | |
| SCHEMBL24802425 | 0.79 | CASP1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019136487-A2 | STEROIDS AND ANTIBODY-CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2019-07-11 | — | — | WO | disclosed |