Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633396 | 0.80 | NPC1 (0.84) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL474757 | 0.80 | ALDH1A1 (0.70) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL27680031 | 0.80 | MAPT (0.56) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL24512443 | 0.80 | PLK1 (0.58) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL3825140 | 0.78 | MAPT (0.68) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL6459176 | 0.78 | NPC1 (0.69) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL17807659 | 0.77 | MAPT (0.71) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL10984145 | 0.77 | ALDH1A1 (0.66) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL6358702 | 0.77 | MAPT (0.60) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 | |
| SCHEMBL13838252 | 0.77 | MAPT (0.60) | MAPTSMN1; SMN2NPC1RAB9ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020257998-A1 | A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD (CN) | 2020-12-30 | — | — | WO | disclosed |