Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 5/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18019596 | 0.84 | NPC1 (0.69) | PLK1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL11774528 | 0.80 | NPC1 (0.59) | PLK1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL10153970 | 0.80 | CACNA1B (0.67) | HDAC2HDAC8HDAC6SMN1; SMN2NPC1 | |
| SCHEMBL22843940 | 0.80 | MAPT (0.59) | SMN1; SMN2NPC1RAB9AHPGDHTT | |
| SCHEMBL10155589 | 0.80 | ALDH1A1 (0.62) | PLK1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL15798566 | 0.78 | HDAC2 (0.55) | PLK1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL250247 | 0.78 | HDAC6 (0.80) | PLK1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL8306146 | 0.77 | HDAC2 (0.64) | PLK1HDAC2HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL12200275 | 0.77 | RAB9A (0.85) | SMN1; SMN2NPC1RAB9AHPGDTP53 | |
| SCHEMBL16610324 | 0.77 | CACNA1B (0.73) | HDAC2HDAC8HDAC6SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022125673-A1 | CELL-PENETRATING PEPTIDES AND PEPTIDE COMPLEXES AND METHODS OF USE | FRED HUTCHINSON CANCER RESEARCH CENTER (US) | 2022-06-16 | — | — | WO | disclosed |