Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.69 |
| ▸ | RAB9A | P51151 | 8/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.67 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.66 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | APEX1 | P27695 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771885 | 0.94 | KMT2A (0.63) | NPC1RAB9AKMT2APOLBMAPT | |
| SCHEMBL13986883 | 0.94 | CACNA1B (0.76) | NPC1RAB9AKMT2APOLBMAPT | |
| SCHEMBL4085808 | 0.92 | SNCA (0.64) | NPC1RAB9AKMT2APOLBMAPT | |
| SCHEMBL7592024 | 0.92 | KMT2A (0.81) | NPC1RAB9AKMT2APOLBMAPT | |
| SCHEMBL8978184 | 0.92 | KMT2A (0.61) | NPC1RAB9AKMT2APOLBMAPT | |
| SCHEMBL13719113 | 0.92 | RAB9A (0.85) | NPC1RAB9AKMT2APOLBMAPT | |
| SCHEMBL8978050 | 0.92 | KMT2A (0.61) | NPC1RAB9AKMT2APOLBMAPT | |
| SCHEMBL5973851 | 0.91 | NPC1 (0.65) | NPC1RAB9AKMT2APOLBMAPT | |
| SCHEMBL24426120 | 0.90 | KMT2A (0.65) | NPC1RAB9AKMT2APOLBMAPT | |
| SCHEMBL6227123 | 0.90 | PTPN1 (0.73) | NPC1RAB9AKMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187409-A1 | Inhibitors of RNase P proteins as antibacterial compounds | POWERS GORDON D (US) | 2005-08-25 | — | — | US | disclosed |
| WO-2005039494-A2 | INHIBITORS OF RNASE P PROTEINS AS ANTIBACTERIAL COMPOUNDS | MESSAGE PHARMACEUTICALS, INC. (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187409-A1 | Inhibitors of RNase P proteins as antibacterial compounds | RNASEH1, RNASEL, RNASE1 | NPC1 2983/4885RAB9A 2257/4885KMT2A 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.