Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 5/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.64 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.64 |
| ▸ | GSK3B | P49841 | 6/20 | 0.58 |
| ▸ | CDK2 | P24941 | 4/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.58 |
| ▸ | JAK2 | O60674 | 2/20 | 0.58 |
| ▸ | CDK1 | P06493 | 2/20 | 0.58 |
| ▸ | SYK | P43405 | 2/20 | 0.58 |
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | CDC7 | O00311 | 1/20 | 0.58 |
| ▸ | PLK4 | O00444 | 1/20 | 0.58 |
| ▸ | IKBKB | O14920 | 1/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | CHUK | O15111 | 1/20 | 0.58 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.58 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.58 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28776128 | 0.85 | PIK3CG (0.66) | PIK3CGPIK3CAPIK3CBGSK3BCDK2 | |
| SCHEMBL2282078 | 0.85 | CDK2 (0.58) | PIK3CGPIK3CAPIK3CBCDK2CDK5 | |
| SCHEMBL2287308 | 0.85 | CDK2 (0.58) | PIK3CGPIK3CAPIK3CBCDK2CDK5 | |
| SCHEMBL2286397 | 0.84 | CDK2 (0.53) | GSK3BCDK2DYRK1AJAK2CDK1 | |
| SCHEMBL7468136 | 0.82 | PIK3CG (0.68) | PIK3CGPIK3CAPIK3CBGSK3BCDK2 | |
| SCHEMBL2284149 | 0.81 | IKBKB (0.53) | PIK3CGGSK3BCDK2JAK2CDK1 | |
| SCHEMBL7468142 | 0.81 | PIK3CG (0.67) | PIK3CGPIK3CAPIK3CBGSK3BCDK2 | |
| SCHEMBL2281181 | 0.81 | PIK3CG (0.58) | PIK3CGPIK3CAPIK3CBGSK3BCDK2 | |
| SCHEMBL28776135 | 0.81 | IKBKB (0.52) | PIK3CGGSK3BCDK2JAK2CDK1 | |
| SCHEMBL2281760 | 0.80 | CDK2 (0.58) | PIK3CGPIK3CAPIK3CBGSK3BCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
| CN-101309586-A | Thiazole compounds as fungicides | BAYER CROPSCIENCE AG (DE) | 2008-11-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | PIK3CG 4241/4885PIK3CA 3293/4885PIK3CB 4206/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | PIK3CG 4256/4885PIK3CA 3359/4885PIK3CB 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.