Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF2 | P09038 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | IDUA | P35475 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.35 |
| ▸ | BDNF | P23560 | 3/20 | 0.35 |
| ▸ | PTN | P21246 | 2/20 | 0.35 |
| ▸ | MDK | P21741 | 2/20 | 0.35 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24239941 | 1.00 | FGF2 (0.40) | FGF2AKT1IDUAALDH1A1MAPT | |
| SCHEMBL13346936 | 0.88 | AMY1A (0.38) | FGF2AKT1IDUAALDH1A1MAPT | |
| SCHEMBL22026382 | 0.87 | IGF2R (0.48) | FGF2MAPTHPSEAMY1AIGF2R | |
| SCHEMBL30153661 | 0.86 | FGF2 (0.37) | FGF2AKT1IDUAALDH1A1MAPT | |
| SCHEMBL23824774 | 0.83 | FGF2 (0.41) | FGF2AKT1IDUAALDH1A1KDM4E | |
| SCHEMBL21385960 | 0.82 | F10 (0.40) | FGF2AKT1IDUAALDH1A1KDM4E | |
| SCHEMBL16188178 | 0.82 | F10 (0.40) | FGF2AKT1IDUAALDH1A1KDM4E | |
| SCHEMBL21233358 | 0.82 | CD209 (0.41) | FGF2ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL21233263 | 0.82 | CD209 (0.41) | FGF2ALDH1A1ALOX15MAPK1HSD17B10 | |
| SCHEMBL21030251 | 0.81 | AKT1 (0.40) | FGF2AKT1IDUAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043833-B2 | Targeted compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-23 | — | — | US | disclosed |
| US-20200407724-A1 | TARGETED COMPOSITIONS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-12-31 | — | — | US | disclosed |