Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4073158 | 0.84 | TSHR (0.46) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL13907638 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL23873858 | 0.82 | LPAR5 (0.38) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL4074514 | 0.79 | TSHR (0.43) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL13191295 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL16004180 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL13190990 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1MAPTHTTLMNA | |
| SCHEMBL9197811 | 0.77 | EPHX1 (0.33) | KDM4EALDH1A1MAPTHTTEPHX1 | |
| SCHEMBL304203 | 0.77 | TDP1 (0.54) | KDM4EALDH1A1MAPTLMNATDP1 | |
| SCHEMBL538207 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1MAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11642217-B2 | Intraocular lens compositions | ALCON INC. (CH) | 2023-05-09 | — | — | US | disclosed |
| US-20200405474-A1 | INTRAOCULAR LENS COMPOSITIONS | ALCON RESEARCH, LTD. | 2020-12-31 | — | — | US | disclosed |