Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251061 | 0.93 | OPRM1 (0.36) | OPRM1SPHK1SLC1A2SLC1A1 | |
| SCHEMBL21668004 | 0.76 | OPRM1 (0.41) | OPRM1SPHK1TP53LMNAHTT | |
| SCHEMBL24004513 | 0.76 | FDPS (0.39) | OPRM1LMNA | |
| SCHEMBL28173817 | 0.76 | FDPS (0.39) | OPRM1LMNA | |
| SCHEMBL9711420 | 0.76 | OPRM1 (0.41) | OPRM1SPHK1TP53LMNAHTT | |
| SCHEMBL10770402 | 0.75 | CYP17A1 (0.44) | OPRM1CYP2D6PLA2G1BPLA2G2ACYP1A2 | |
| SCHEMBL3796989 | 0.74 | GPR84 (0.42) | SPHK1TP53CYP2D6GMNNLMNA | |
| SCHEMBL28189919 | 0.74 | OPRM1 (0.39) | OPRM1SPHK1LMNAHTT | |
| SCHEMBL27813576 | 0.74 | OPRM1 (0.39) | OPRM1SPHK1LMNAHTT | |
| SCHEMBL28090871 | 0.74 | OPRM1 (0.39) | OPRM1SPHK1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998726-B2 | Method for fixing a protein on a pyrrole-based polymer and use thereof for making a sensor | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2011-08-16 | — | — | US | disclosed |
| EP-1563304-B1 | METHOD FOR FIXING A PROTEIN ON A PYRROLE-BASED POLYMER AND USE THEREOF FOR MAKING A SENSOR | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-09-15 | — | — | EP | disclosed |
| US-20060035208-A1 | Method for fixing a protein on a pyrrole-based polymer and use thereof for making a sensor | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2006-02-16 | — | — | US | disclosed |
| EP-1563304-A1 | METHOD FOR FIXING A PROTEIN ON A PYRROLE-BASED POLYMER AND USE THEREOF FOR MAKING A SENSOR | Commissariat A L'Energie Atomique (FR) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004048972-A1 | METHOD FOR FIXING A PROTEIN ON A PYRROLE-BASED POLYMER AND USE THEREOF FOR MAKING A SENSOR | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2004-06-10 | — | — | WO | disclosed |