SCHEMBL25850882

SCHEMBL25850882

BN1/C(=C/C=C2\C(=O)c3ccccc3C2=C(C#N)C#N)C(C)(C)c2c1ccc1ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 7/20 0.34
KMT2A Q03164 5/20 0.34
MEN1 O00255 4/20 0.34
MAPT P10636 4/20 0.34
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPC1 O15118 1/20 0.34
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
RAB9A P51151 1/20 0.34
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
MAPK1 P28482 1/20 0.31
PRMT5 O14744 1/20 0.31
PRMT8 Q9NR22 1/20 0.31
DNMT1 P26358 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MLNR O43193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849800 0.90 KMT2A (0.42) PRMT1KMT2AMEN1MAPTHTT
SCHEMBL25165432 0.83 PRMT1 (0.31) PRMT1KMT2AMEN1MAPTHTT
SCHEMBL22848191 0.83 PRMT1 (0.31) PRMT1KMT2AMEN1MAPTHTT
SCHEMBL25850890 0.78 DNMT1 (0.32) MAPTDNMT1ALDH1A1
SCHEMBL26302864 0.78 MEN1 (0.37) PRMT1KMT2AMEN1MAPTHTT
SCHEMBL25850879 0.75 MEN1 (0.45) KMT2AMEN1MAPTHTTSMN1; SMN2
SCHEMBL12217153 0.74 MAPT (0.61) KMT2AMEN1MAPTHTTSMN1; SMN2
SCHEMBL25849806 0.73 ALDH1A1 (0.33) PRMT1KMT2AMEN1MAPTPOLB
SCHEMBL25849795 0.70 MAPT (0.45) PRMT1KMT2AMEN1MAPTHTT
SCHEMBL21419168 0.70 PRMT1 (0.38) PRMT1KMT2AMEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 US disclosed