SCHEMBL17880362

SCHEMBL17880362

Cc1cc(C)c(Nc2ccc3c(ccc4ccccc43)c2)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 16/20 0.53
CYP1A2 P05177 2/20 0.50
CYP2A6 P11509 1/20 0.50
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KDM1A O60341 1/20 0.44
MAPK14 Q16539 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22848405 0.86 RAPGEF4 (0.60) RAPGEF4ALDH1A1HPGDHSD17B10
SCHEMBL18134975 0.81 HPGD (0.53) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL19533724 0.80 ALDH1A1 (0.59) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL22848481 0.78 RAPGEF4 (0.68) RAPGEF4CYP1A2CYP2A6
SCHEMBL19763110 0.77 CDC25B (0.49) CYP1A2ALDH1A1HPGDHSD17B10KDM1A
SCHEMBL24029998 0.77 ALDH1A1 (0.67) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL22848171 0.77 ALDH1A1 (0.52) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL28194328 0.77 CYP1A2 (0.53) RAPGEF4CYP1A2CYP2A6ALDH1A1HPGD
SCHEMBL23765045 0.75 ALDH1A1 (0.59) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL16657696 0.75 ALDH1A1 (0.70) CYP2A6ALDH1A1HPGDHSD17B10MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793063-B2 Condensed-cyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-17 US disclosed
US-11793063-B2 Condensed-cyclic compound and organic light emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-10-17 US disclosed
US-20160190450-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190450-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793063-B2 Condensed-cyclic compound and organic light emitting device including the same CRY1, CRY2, CCNE2 RAPGEF4 3624/4885CYP1A2 1346/4885CYP2A6 2286/4885
US-20160190450-A1 CONDENSED-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 RAPGEF4 3624/4885CYP1A2 1346/4885CYP2A6 2286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.