Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25511104 | 0.77 | — | — | |
| SCHEMBL23903683 | 0.75 | ALDH1A1 (0.34) | ALDH1A1TDP1HSD17B10CRBN | |
| SCHEMBL14775319 | 0.72 | — | — | |
| SCHEMBL6140627 | 0.69 | — | — | |
| SCHEMBL13749214 | 0.67 | — | — | |
| SCHEMBL16091195 | 0.67 | — | — | |
| SCHEMBL21208249 | 0.67 | CRBN (0.46) | TDP1CRBN | |
| SCHEMBL22810802 | 0.67 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL19869376 | 0.66 | ALDH1A1 (0.41) | ALDH1A1TDP1HSD17B10 | |
| SCHEMBL28768793 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200407323-A1 | PROCESS FOR THE PREPARATION OF IVACAFTOR AND ITS ITERMEDIATES | LAURUS LABS LIMITED (IN) | 2020-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200407323-A1 | PROCESS FOR THE PREPARATION OF IVACAFTOR AND ITS ITERMEDIATES | ACVR1, SLC10A2, CYP4A11 | ALDH1A1 1022/4885TDP1 2758/4885HSD17B10 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.