SCHEMBL22849566

SCHEMBL22849566

O=C(CC(O)CCc1ccccc1)NO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 3/20 0.58
HDAC6 Q9UBN7 3/20 0.58
HDAC2 Q92769 3/20 0.58
MMP2 P08253 4/20 0.57
MMP12 P39900 3/20 0.57
MMP9 P14780 2/20 0.57
MMP14 P50281 2/20 0.57
MMP13 P45452 2/20 0.57
DPP4 P27487 1/20 0.56
HDAC1 Q13547 6/20 0.54
HDAC3 O15379 1/20 0.54
HDAC5 Q9UQL6 1/20 0.54
TSHR P16473 1/20 0.54
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ALOX5 P09917 1/20 0.51
MMP1 P03956 4/20 0.51
MMP3 P08254 2/20 0.51
CNR2 P34972 1/20 0.50
FCER2 P06734 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23080168 0.83 MMP2 (0.54) MMP2MMP12MMP9MMP14MMP13
SCHEMBL687094 0.82 MMP12 (0.80) MMP2MMP12MMP9MMP14MMP13
SCHEMBL8333817 0.82 MMP12 (0.80) MMP2MMP12MMP9MMP14MMP13
SCHEMBL4745347 0.82 MMP12 (0.80) MMP2MMP12MMP9MMP14MMP13
SCHEMBL29016765 0.81 HDAC8 (0.67) HDAC8HDAC6HDAC2MMP2MMP12
SCHEMBL3320743 0.81 HDAC2 (0.56) HDAC8HDAC6HDAC2MMP2MMP12
SCHEMBL404324 0.80 MMP1 (0.49) HDAC8HDAC6HDAC2MMP2MMP12
SCHEMBL11911570 0.80 DPP4 (0.54) MMP2MMP12MMP9MMP14MMP13
SCHEMBL15522837 0.80 HDAC8 (0.62) HDAC8HDAC6HDAC2MMP2MMP12
SCHEMBL6444313 0.79 MMP12 (0.60) MMP2MMP12MMP9MMP14MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020263995-A1 HYDROXAMIC ACIDS COMPRISING PYRAZOLE MOIETY AND USES THEREOF HAWAII BIOTECH, INC. (US) 2020-12-30 WO disclosed