SCHEMBL2285010

SCHEMBL2285010

[CH2]OC(CCCCCCCCCC)CN[C]=O

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.35
EPHX1 P07099 2/20 0.34
MAPT P10636 1/20 0.34
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
SMPD1 P17405 3/20 0.33
GPR84 Q9NQS5 3/20 0.32
FDPS P14324 3/20 0.32
FFAR1 O14842 1/20 0.32
TLR2 O60603 2/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6454885 0.80 ADH1B (0.39) ZDHHC7EPHX1MAPTLCKPPARD
SCHEMBL6433902 0.77 LMNA (0.42) SMPD1GPR84FDPSFFAR1LMNA
SCHEMBL3140911 0.76 LMNA (0.45) ZDHHC7MAPTLCKPPARDZDHHC20
SCHEMBL6434042 0.75 DNM1 (0.46) SMPD1GPR84FDPSLMNA
SCHEMBL10461986 0.74 ACE2 (0.44) ZDHHC7MAPTLCKPPARDZDHHC20
SCHEMBL6450096 0.74 SMPD1 (0.38) ZDHHC7MAPTLCKPPARDZDHHC20
SCHEMBL6434217 0.73 LMNA (0.39) SMPD1GPR84FDPSFFAR1LMNA
SCHEMBL6436127 0.73 LMNA (0.39) SMPD1GPR84FDPSFFAR1LMNA
SCHEMBL6437008 0.73 LMNA (0.39) SMPD1GPR84FDPSFFAR1LMNA
SCHEMBL6436352 0.73 LMNA (0.39) SMPD1GPR84FDPSFFAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US claimed
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 EP claimed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 WO claimed
EP-1525182-A1 PHOTOACTIVE MATERIALS Rolic AG (CH) 2005-04-27 EP disclosed
WO-2004013086-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2004-02-12 WO disclosed