Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.71 |
| ▸ | MIF | P14174 | 1/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 4/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180735 | 0.83 | FLT3 (1.00) | FLT3MIFPIK3CAKDRDYRK1A | |
| SCHEMBL29109646 | 0.79 | FLT3 (0.69) | FLT3MIFPIK3CAKDRDYRK1A | |
| SCHEMBL30655418 | 0.79 | FLT3 (0.69) | FLT3MIFPIK3CAKDRDYRK1A | |
| SCHEMBL2650330 | 0.79 | FLT3 (0.74) | FLT3MIFPIK3CAKDRDYRK1A | |
| SCHEMBL25261576 | 0.77 | FLT3 (0.71) | FLT3MIFPIK3CAKDRDYRK1A | |
| SCHEMBL23051047 | 0.77 | FLT3 (0.71) | FLT3MIFPIK3CAKDRPKM | |
| SCHEMBL15757217 | 0.76 | FLT3 (0.69) | FLT3MIFPIK3CAKDRDYRK1A | |
| SCHEMBL26178951 | 0.76 | PIK3CA (0.56) | FLT3PIK3CAKDRDYRK1AMAP2K1 | |
| SCHEMBL29822550 | 0.75 | KDR (0.68) | FLT3MIFPIK3CAKDRDYRK1A | |
| SCHEMBL15757581 | 0.75 | FLT3 (0.68) | FLT3MIFPIK3CAKDRDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020263187-A1 | COMPOUNDS FOR TREATMENT OF EYE DISORDERS | SINOPSEE THERAPEUTICS (SG) | 2020-12-30 | — | — | WO | disclosed |