Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.74 |
| ▸ | KDR | P35968 | 5/20 | 0.66 |
| ▸ | MIF | P14174 | 1/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.59 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | PRKACA | P17612 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.59 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.59 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.59 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.59 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.59 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25789349 | 0.90 | FLT3 (0.67) | FLT3KDRMIFDYRK1ACHEK1 | |
| SCHEMBL25789355 | 0.88 | FLT3 (0.65) | FLT3KDRMIFDYRK1ACHEK1 | |
| SCHEMBL15757581 | 0.87 | FLT3 (0.68) | FLT3KDRMIFDYRK1ACHEK1 | |
| SCHEMBL23051047 | 0.85 | FLT3 (0.71) | FLT3KDRMIFPIK3CAPKM | |
| SCHEMBL13180735 | 0.85 | FLT3 (1.00) | FLT3KDRMIFDYRK1APIK3CA | |
| SCHEMBL25261576 | 0.85 | FLT3 (0.71) | FLT3KDRMIFDYRK1ACHEK1 | |
| SCHEMBL29822550 | 0.84 | KDR (0.68) | FLT3KDRMIFDYRK1ACHEK1 | |
| SCHEMBL25789350 | 0.82 | MIF (0.57) | FLT3KDRMIFDYRK1ACHEK1 | |
| SCHEMBL30655418 | 0.81 | FLT3 (0.69) | FLT3KDRMIFDYRK1ACHEK1 | |
| SCHEMBL73445 | 0.81 | MIF (0.60) | FLT3KDRMIFDYRK1ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070905-A1 | Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity | UNIV DE VELENCIA (ES) | 2026-03-12 | — | — | US | claimed |
| WO-2025003545-A1 | DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY | UNIVERSITAT DE VALÈNCIA (ES) | 2025-01-02 | — | — | WO | claimed |
| US-20260070905-A1 | Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity | UNIV DE VELENCIA (ES) | 2026-03-12 | — | — | US | disclosed |
| WO-2025003545-A1 | DERIVATIVES OF IMIDAZO[1,2-A]PYRIDINE WITH ANTI-INFLAMMATORY ACTIVITY | UNIVERSITAT DE VALÈNCIA (ES) | 2025-01-02 | — | — | WO | disclosed |
| CN-117003750-A | Green synthesis method of imidazo [1,2-a ] pyridine compound | 台州学院 | 2023-11-07 | — | — | CN | disclosed |
| US-11133473-B2 | Condensed cyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-09-28 | — | — | US | disclosed |
| EP-2872491-B1 | INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR | BLUEPRINT MEDICINES CORP (US) | 2021-05-05 | — | — | EP | disclosed |
| US-10930853-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
| US-10196436-B2 | Inhibitors of the fibroblast growth factor receptor | BLUEPRINT MEDICINES CORPORATION (US) | 2019-02-05 | — | — | US | disclosed |
| US-9868722-B2 | Monocyclic pyrimidine/pyridine compounds as inhibitors of P97 complex | CLEAVE BIOSCIENCES, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| EP-2900238-B1 | FUSED HETEROCYCLIC COMPOUNDS AS SELECTIVE BMP INHIBITORS | UNIV VANDERBILT (US) | 2017-12-06 | — | — | EP | disclosed |
| EP-1511747-B1 | IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME (GB) | 2006-04-12 | — | — | EP | disclosed |
| US-20060040940-A1 | Imidazopyridines pyrimidines and triazines for enhancing cognition as gaba-a-alphas 5 receoptor subtype ligands | BETTATI MICHELA | 2006-02-23 | — | — | US | disclosed |
| US-6872731-B2 | Imidazo-pyridine derivatives as ligands for GABA receptors | MERCK SHARP & DOHME LTD. (GB) | 2005-03-29 | — | — | US | disclosed |
| WO-2004076452-A1 | 5,8-DIFLUOROIMIDAZO[1,2-a]PYRIDINES AS GABA-A α2/α3 LIGANDS FOR TREATING ANXIETY AND/OR DEPRESSION | MERCK SHARP & DOHME LIMITED (GB) | 2004-09-10 | — | — | WO | disclosed |
| EP-1235827-B1 | IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME (GB) | 2004-07-07 | — | — | EP | disclosed |
| US-20020188000-A1 | Imidazo-pyridine derivatives as ligands for gaba receptors | MERCK SHARP & DOHME LTD. (GB) | 2002-12-12 | — | — | US | disclosed |
| EP-1235827-A2 | IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LTD. (GB) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038326-A3 | IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME (GB) | 2002-05-10 | — | — | WO | disclosed |
| WO-2001038326-A2 | IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 2001-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11133473-B2 | Condensed cyclic compound and organic light-emitting device including the same | C1S, C1R, CCNA1 | FLT3 4387/4885KDR 3036/4885MIF 4374/4885 |
| US-10196436-B2 | Inhibitors of the fibroblast growth factor receptor | FGFR1, FGFR2, FGFR3 | FLT3 34/4885KDR 37/4885MIF 736/4885 |
| US-20060040940-A1 | Imidazopyridines pyrimidines and triazines for enhancing cognition as gaba-a-alphas 5 receoptor subtype ligands | CHRNA3, GABRA3, GABRB3 | FLT3 1937/4885KDR 1366/4885MIF 3787/4885 |
| US-20020188000-A1 | Imidazo-pyridine derivatives as ligands for gaba receptors | GABRA3, GABRA2, GABRA1 | FLT3 1021/4885KDR 1703/4885MIF 4602/4885 |
| US-20260070905-A1 | Derivatives of Imidazo[1,2-A]Pyridine with Anti-Inflammatory Activity | IL1A, IL6, IL1B | FLT3 4415/4885KDR 1550/4885MIF 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.