Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.69 |
| ▸ | MIF | P14174 | 1/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30655418 | 1.00 | FLT3 (0.69) | FLT3MIFPIK3CAPKMKDR | |
| SCHEMBL13180735 | 0.82 | FLT3 (1.00) | FLT3MIFPIK3CAPKMKDR | |
| SCHEMBL2650330 | 0.81 | FLT3 (0.74) | FLT3MIFPIK3CAPKMKDR | |
| SCHEMBL14138786 | 0.81 | MIF (0.60) | FLT3MIFPIK3CAPKMKDR | |
| SCHEMBL73445 | 0.81 | MIF (0.60) | FLT3MIFPIK3CAPKMKDR | |
| SCHEMBL73247 | 0.81 | BACE1 (0.62) | FLT3MIFPIK3CAKDREGLN2 | |
| SCHEMBL22851709 | 0.79 | FLT3 (0.71) | FLT3MIFPIK3CAPKMKDR | |
| SCHEMBL25789350 | 0.79 | MIF (0.57) | FLT3MIFPIK3CAPKMKDR | |
| SCHEMBL72363 | 0.78 | IRAK4 (0.61) | FLT3MIFPIK3CAPKMKDR | |
| SCHEMBL14098511 | 0.78 | MIF (0.56) | FLT3MIFPIK3CAPKMKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003750-A | Green synthesis method of imidazo [1,2-a ] pyridine compound | 台州学院 | 2023-11-07 | — | — | CN | disclosed |