Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 3/20 | 0.57 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.49 |
| ▸ | LIPC | P11150 | 1/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294370 | 1.00 | MPO (0.57) | MPOTAS2R14LIPCLIPGAKR1C3 | |
| SCHEMBL30294337 | 0.91 | TAS2R14 (0.51) | MPOTAS2R14LIPCLIPGAKR1C3 | |
| SCHEMBL30294690 | 0.88 | FABP3 (0.50) | MPOAKR1C3AKR1C2DHODHP2RY4 | |
| SCHEMBL22852866 | 0.88 | FABP3 (0.50) | MPOAKR1C3AKR1C2DHODHP2RY4 | |
| SCHEMBL22853053 | 0.84 | MRGPRX4 (0.42) | MPOTAS2R14 | |
| SCHEMBL30294656 | 0.84 | MRGPRX4 (0.42) | MPOTAS2R14 | |
| SCHEMBL22833319 | 0.83 | MPO (0.61) | MPOTAS2R14LIPCLIPGAKR1C3 | |
| SCHEMBL29383283 | 0.83 | MPO (0.61) | MPOTAS2R14LIPCLIPGAKR1C3 | |
| SCHEMBL22853108 | 0.82 | MPO (0.44) | MPOTAS2R14LIPCLIPGAKR1C3 | |
| SCHEMBL30294675 | 0.82 | MPO (0.44) | MPOTAS2R14LIPCLIPGAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |