Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | FABP3 | P05413 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.48 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.48 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294397 | 1.00 | KDM4E (0.54) | KDM4EHSD17B10FABP3FABP4P2RY4 | |
| SCHEMBL22852841 | 0.90 | CLCN2 (0.57) | KDM4EHSD17B10FABP3FABP4MAPT | |
| SCHEMBL30294548 | 0.90 | CLCN2 (0.57) | KDM4EHSD17B10FABP3FABP4MAPT | |
| SCHEMBL22853383 | 0.90 | P2RY4 (0.56) | FABP3FABP4P2RY4KMT2AFTO | |
| SCHEMBL30294653 | 0.90 | P2RY4 (0.56) | FABP3FABP4P2RY4KMT2AFTO | |
| SCHEMBL31521818 | 0.86 | KMT2A (0.53) | MAPTKMT2AALDH1A1MAPK13MAPK12 | |
| SCHEMBL22852994 | 0.85 | DHODH (0.56) | FABP3FABP4P2RY4KMT2AAKR1C3 | |
| SCHEMBL30294529 | 0.85 | DHODH (0.56) | FABP3FABP4P2RY4KMT2AAKR1C3 | |
| SCHEMBL22853082 | 0.83 | CLCN2 (0.53) | FABP3FABP4P2RY4MAPTFTO | |
| SCHEMBL22853345 | 0.83 | KDM4E (0.51) | KDM4EHSD17B10FABP3FABP4P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |