Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 8/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294647 | 0.89 | CLCN2 (0.53) | MEN1KMT2AMAPK1CLCN2FABP3 | |
| SCHEMBL22853082 | 0.84 | CLCN2 (0.53) | CLCN2FABP3FABP4DHODHIDO1 | |
| SCHEMBL30294669 | 0.84 | CLCN2 (0.53) | CLCN2FABP3FABP4DHODHIDO1 | |
| SCHEMBL26922880 | 0.82 | MAP2K1 (0.48) | MEN1KMT2ACLCN2FABP3FABP4 | |
| SCHEMBL22853121 | 0.77 | IDO1 (0.48) | MEN1KMT2AMAPK1CLCN2FABP3 | |
| SCHEMBL22852994 | 0.77 | DHODH (0.56) | MEN1KMT2AMAPK1FABP3FABP4 | |
| SCHEMBL30294377 | 0.77 | IDO1 (0.48) | MEN1KMT2AMAPK1CLCN2FABP3 | |
| SCHEMBL30294529 | 0.77 | DHODH (0.56) | MEN1KMT2AMAPK1FABP3FABP4 | |
| SCHEMBL22853085 | 0.77 | AKR1C2 (0.46) | DHODHFTO | |
| SCHEMBL30294438 | 0.77 | AKR1C2 (0.46) | DHODHFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |