Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.59 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.47 |
| ▸ | MPO | P05164 | 3/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30294773 | 1.00 | TAS2R14 (0.59) | TAS2R14CLCN2GRIK1SORT1MPO | |
| SCHEMBL22833402 | 0.85 | TAS2R14 (0.61) | TAS2R14CLCN2GRIK1MPOAKR1C3 | |
| SCHEMBL29380178 | 0.85 | TAS2R14 (0.61) | TAS2R14CLCN2GRIK1MPOAKR1C3 | |
| SCHEMBL22852772 | 0.84 | KDM4E (0.44) | TAS2R14KDM4ECYP2C19 | |
| SCHEMBL30294611 | 0.84 | KDM4E (0.44) | TAS2R14KDM4ECYP2C19 | |
| SCHEMBL22853391 | 0.83 | TAS2R14 (0.52) | TAS2R14SORT1MPOAKR1C3AKR1C2 | |
| SCHEMBL30294713 | 0.83 | TAS2R14 (0.52) | TAS2R14SORT1MPOAKR1C3AKR1C2 | |
| SCHEMBL22852832 | 0.79 | MPO (0.58) | TAS2R14GRIK1MPOAKR1C3AKR1C2 | |
| SCHEMBL30294413 | 0.79 | MPO (0.58) | TAS2R14GRIK1MPOAKR1C3AKR1C2 | |
| SCHEMBL14670349 | 0.77 | TAS2R14 (0.68) | TAS2R14GRIK1SORT1MPOAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020261114-A1 | 2,3-DIHYDROQUINAZOLIN COMPOUNDS AS NAV1.8 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-12-30 | — | — | WO | disclosed |