SCHEMBL2285393

SCHEMBL2285393

O=COCCCCCCCCO

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
ACHE P22303 6/20 0.34
LMNA P02545 2/20 0.33
ALDH1A1 P00352 2/20 0.33
TSHR P16473 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
APP P05067 2/20 0.31
CYP3A4 P08684 1/20 0.31
PRKCA P17252 1/20 0.30
THRB P10828 1/20 0.30
HTT P42858 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2280925 1.00 GAA (0.36) GAAGPR84FFAR1FFAR4ACHE
SCHEMBL2283367 1.00 GAA (0.36) GAAGPR84FFAR1FFAR4ACHE
SCHEMBL28554252 1.00 GAA (0.36) GAAGPR84FFAR1FFAR4ACHE
SCHEMBL2285364 1.00 GAA (0.36) GAAGPR84FFAR1FFAR4ACHE
SCHEMBL303934 1.00
SCHEMBL2286776 1.00 GAA (0.36) GAAGPR84FFAR1FFAR4ACHE
SCHEMBL2284493 1.00 GAA (0.36) GAAGPR84FFAR1FFAR4ACHE
SCHEMBL2281635 1.00 GAA (0.36) GAAGPR84FFAR1FFAR4ACHE
SCHEMBL302819 0.97
Ethylene SCHEMBL27540279 0.92 GAA (0.31) GAAALDH1A1TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US claimed
US-7750185-B2 Photoactive materials ROLIC AG (CH) 2010-07-06 US claimed
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked ROLIC AG (CH) 2005-12-29 US claimed
EP-1386910-A1 Photoactive materials Rolic AG (CH) 2004-02-04 EP claimed
EP-1525182-B1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2016-04-06 EP disclosed
US-8436132-B2 Photoactive materials ROLIC AG (CH) 2013-05-07 US disclosed
US-20110236602-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2011-09-29 US disclosed
US-7994273-B2 Photoactive materials ROLIC AG (CH) 2011-08-09 US disclosed
US-20100272979-A1 PHOTOACTIVE MATERIALS ROLIC AG (CH) 2010-10-28 US disclosed
US-7750185-B2 Photoactive materials ROLIC AG (CH) 2010-07-06 US disclosed
US-7160658-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2007-01-09 US disclosed
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked ROLIC AG (CH) 2005-12-29 US disclosed
US-6936388-B2 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2005-08-30 US disclosed
US-20050170272-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2005-08-04 US disclosed
EP-1386910-A1 Photoactive materials Rolic AG (CH) 2004-02-04 EP disclosed
US-20030077531-A1 Electrophotographic photoreceptor, and image forming method, image forming apparatus, and image forming apparatus processing unit using same RICOH COMPANY, LTD. (JP) 2003-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110236602-A1 PHOTOACTIVE MATERIALS AOC1, CRY1, CCNA1 GAA 3006/4885GPR84 3003/4885FFAR1 4437/4885
US-20050288480-A1 Liquid crystals adjustment layers containing diamine compound; polyamic acid or polyimides; crosslinked C9, F12, DAO GAA 3752/4885GPR84 3503/4885FFAR1 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.