Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25825947 | 0.98 | LMNA (0.46) | LMNACYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL25826743 | 0.93 | CYP1A2 (0.43) | LMNACYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL25827992 | 0.89 | CYP1A2 (0.41) | LMNACYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL21116081 | 0.84 | BDKRB2 (0.39) | LMNACYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL22856954 | 0.81 | CYP1A2 (0.54) | CYP1A2CYP2D6CYP2C19CNR2TAAR1 | |
| SCHEMBL21115738 | 0.79 | SLC6A4 (0.38) | LMNATNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL25825352 | 0.78 | CYP1A2 (0.43) | LMNACYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL20706282 | 0.77 | TSHR (0.58) | L3MBTL1TNNC1S1PR1SGPL1S1PR4 | |
| SCHEMBL4191545 | 0.77 | ESR1 (0.63) | LMNACYP1A2CYP2D6CYP2C19NPC1 | |
| SCHEMBL3178688 | 0.77 | ESR1 (0.63) | LMNACYP1A2CYP2D6CYP2C19NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10882871-B2 | 18/19F-labelled compounds which target the prostate specific membrane antigen | BRITISH COLUMBIA CANCER AGENCY BRANCH | 2021-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10882871-B2 | 18/19F-labelled compounds which target the prostate specific membrane antigen | KLK3, FOLH1, FOLR1 | LMNA 3766/4885CYP1A2 3426/4885CYP2D6 2577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.