Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.50 |
| ▸ | CNR1 | P21554 | 8/20 | 0.50 |
| ▸ | CNR2 | P34972 | 8/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22859155 | 1.00 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1HDAC3 | |
| SCHEMBL22858805 | 1.00 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1HDAC3 | |
| SCHEMBL22858735 | 0.96 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1 | |
| SCHEMBL30526487 | 0.96 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1 | |
| SCHEMBL4341647 | 0.96 | TRPV1 (0.50) | TRPV1CNR1CNR2L3MBTL1 | |
| SCHEMBL22858818 | 0.89 | TRPV1 (0.53) | TRPV1CNR1CNR2L3MBTL1HDAC3 | |
| SCHEMBL775241 | 0.88 | L3MBTL1 (0.48) | TRPV1CNR1CNR2L3MBTL1HDAC3 | |
| SCHEMBL30526484 | 0.86 | TRPV1 (0.60) | TRPV1CNR1CNR2 | |
| SCHEMBL25069844 | 0.85 | TRPV1 (0.41) | TRPV1CNR1CNR2L3MBTL1MTNR1A | |
| SCHEMBL828065 | 0.85 | TRPV1 (0.41) | TRPV1CNR1CNR2L3MBTL1MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498292-B2 | Combinatorial libraries of autoinducer analogs, autoinducer agonists and antagonists, and methods of use thereof | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2009-03-03 | — | — | US | disclosed |
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-01-31 | — | — | US | disclosed |
| EP-1578359-A2 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | The Research Foundation of the State University of New York (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20040115732-A1 | Combinatorial libraries of autoinducer analogs, autoinducer agonists and antagonists, and methods of use thereof | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | 2004-06-17 | — | — | US | disclosed |
| WO-2004016213-A2 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2004-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027115-A1 | COMBINATORIAL LIBRARIES OF AUTOINDUCER ANALOGS, AUTOINDUCER AGONISTS AND ANTAGONISTS, AND METHODS OF USE THEREOF | QRFPR, CASR, BLVRB | TRPV1 436/4885CNR1 94/4885CNR2 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.