SCHEMBL22859548

SCHEMBL22859548

Cn1nc(C(F)(F)F)cc1OCc1c(S(C)(=O)=O)ccc(C(=O)C2=C(O)CCCC2=O)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
KMT2A Q03164 1/20 0.33
PDE4B Q07343 1/20 0.31
RORC P51449 5/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22859731 0.89 RORC (0.32) RORC
SCHEMBL29736590 0.89 RORC (0.32) RORC
SCHEMBL22859695 0.88 ALDH1A1 (0.34) ALDH1A1KMT2APDE4BRORC
SCHEMBL22859704 0.86
SCHEMBL22859698 0.84 ALDH1A1 (0.35) ALDH1A1KMT2APDE4BRORC
SCHEMBL22859642 0.84 RORC (0.33) ALDH1A1RORC
SCHEMBL22859699 0.83 RORC (0.34) RORC
SCHEMBL22859549 0.82 ALDH1A1 (0.37) ALDH1A1KMT2APDE4BRORC
SCHEMBL22859631 0.81 CRHR1 (0.31) RORC
SCHEMBL22859639 0.80 ALDH1A1 (0.35) ALDH1A1KMT2APDE4BRORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021000736-A1 SUBSTITUTED BENZOYL-PYRAZOLE COMPOUND, AND APPLICATION THEREOF IN AGRICULTURE 东莞市东阳光农药研发有限公司 2021-01-07 WO disclosed