Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20868509 | 0.89 | NOTUM (0.45) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL28934829 | 0.85 | NOTUM (0.49) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL23059425 | 0.85 | NOTUM (0.43) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL22480272 | 0.85 | NOTUM (0.43) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL25884465 | 0.84 | NOTUM (0.42) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL24036185 | 0.84 | NOTUM (0.48) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL20857112 | 0.82 | NOTUM (0.47) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL29065096 | 0.82 | NOTUM (0.47) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL20857079 | 0.82 | NOTUM (0.40) | NOTUMCYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL20857078 | 0.82 | NOTUM (0.40) | NOTUMCYP1A2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002433-A1 | BIOCOMPATIBLE HYDROGEL CAPSULES AND PROCESS FOR PREPARING SAME | SIGILON THERAPEUTICS, INC. | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210002433-A1 | BIOCOMPATIBLE HYDROGEL CAPSULES AND PROCESS FOR PREPARING SAME | ACMSD, ALG1, COL2A1 | NOTUM 1318/4885CYP1A2 4214/4885KDM4E 3426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.