Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24900472 | 0.85 | KDM4E (0.64) | KMT2APKMTLR8CNR2KDM4E | |
| SCHEMBL30957519 | 0.85 | KDM4E (0.64) | KMT2APKMTLR8CNR2KDM4E | |
| SCHEMBL22860192 | 0.81 | CNR2 (0.52) | KMT2ATLR8NLRP3CNR2CYP1A2 | |
| SCHEMBL12082609 | 0.81 | KMT2A (0.72) | KMT2ATLR8NLRP3KDM4ERAD52 | |
| SCHEMBL15139648 | 0.81 | PKM (0.70) | PKMKDM4ERAB9APOLBTSHR | |
| SCHEMBL18088406 | 0.79 | HDAC1 (0.60) | TLR8CNR2 | |
| SCHEMBL24900462 | 0.79 | MAPT (0.55) | KMT2APKMCNR2TDP1RAB9A | |
| SCHEMBL18731433 | 0.79 | TLR8 (0.51) | PKMTLR8KDM4ECYP1A2TSHR | |
| SCHEMBL10989096 | 0.78 | KDM4E (0.68) | KMT2ATLR8NLRP3KDM4ERAD52 | |
| SCHEMBL13043873 | 0.77 | NLRP3 (0.50) | KMT2ATLR8NLRP3KDM4ERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003314-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-01-07 | — | — | WO | disclosed |