Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22171277 | 0.82 | EPHX1 (0.38) | SIGMAR1EPHX1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL19711741 | 0.77 | SIGMAR1 (0.41) | SIGMAR1EPHX1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL19523725 | 0.74 | SIGMAR1 (0.42) | SIGMAR1EPHX1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL19455741 | 0.72 | SIGMAR1 (0.53) | SIGMAR1EPHX1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL22860279 | 0.71 | EPHX1 (0.42) | SIGMAR1EPHX1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL15189278 | 0.70 | EPHX1 (0.46) | SIGMAR1EPHX1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL11183810 | 0.68 | SIGMAR1 (0.40) | SIGMAR1EPHX1ALDH1A1KDM4EEPHX2 | |
| SCHEMBL24810132 | 0.67 | ALDH1A1 (0.31) | ALDH1A1CYP3A4 | |
| SCHEMBL22594429 | 0.64 | FAAH (0.34) | SIGMAR1ALDH1A1 | |
| SCHEMBL8297620 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020140052-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. (US) | 2020-07-02 | — | — | WO | disclosed |