SCHEMBL2286145

SCHEMBL2286145

Brc1[c]c(Br)ncc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4923576 0.74
SCHEMBL600904 0.74
SCHEMBL4926053 0.74
SCHEMBL4928151 0.74
SCHEMBL4928793 0.74
SCHEMBL210865 0.56
SCHEMBL28083103 0.55 KDM4E (0.41)
SCHEMBL246592 0.54
SCHEMBL31357780 0.54
SCHEMBL383108 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213353-A Aryl-oxazole-oxazoline compound and preparation method and application thereof 贵州大学 2022-03-22 CN claimed
CN-114213353-B Aryl-oxazole-oxazoline compound and preparation method and application thereof 贵州大学 2023-04-14 CN disclosed
CN-114213353-A Aryl-oxazole-oxazoline compound and preparation method and application thereof 贵州大学 2022-03-22 CN disclosed
US-20110201496-A1 Substituted 5-Hetaryl-4-Aminopyrimidines BASF AKTIENGESELLSCHAFT (DE) 2011-08-18 US disclosed
EP-2010514-B1 3-(PYRIDIN-2-YL)-[1,2,4]-TRIAZINES FOR USE AS FUNGICIDES BASF SE (DE) 2010-12-29 EP disclosed
US-20100093738-A1 Fungicidal Compounds and Fungicidal Compositions BASF SE (DE) 2010-04-15 US disclosed
EP-2097412-A2 FUNGICIDAL N-HETEROARYL-CONDENSED PYRIDINE DERIVATIVES AND FUNGICIDAL COMPOSITIONS BASF SE (DE) 2009-09-09 EP disclosed
US-20090111692-A1 3-(Pyridin-2-Yl)-[1,2,4]-Triazines as Fungicides BASF AKTIENGESELLSCHAFT (DE) 2009-04-30 US disclosed
US-20090105072-A1 2-(Pyridin-2-Yl)-Pyrimidines for Use as Fungicides BASF SE (DE) 2009-04-23 US disclosed
WO-2009007187-A1 SUBSTITUTED 5-HETARYLPYRIMIDINES BASF SE (DE) 2009-01-15 WO disclosed
WO-2007110418-A2 SUBSTITUTED 5-HETARYL-4-AMINOPYRIMIDINES BASF SE (DE) 2007-10-04 WO disclosed
WO-2007101870-A1 SUBSTITUTED TRIAZOLOPYRIMIDINES, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE LATTER BASF SE (DE) 2007-09-13 WO disclosed
EP-1401826-B1 PYRAZOLE DERIVATIVES AS HIV REVERSE TRANSCRIPTASE INHIBITORS HOFFMANN LA ROCHE (CH) 2007-03-21 EP disclosed
WO-2006122740-A2 7-AMINO-6-HETARYLIMIDAZOLO[1,2-A]PYRIMIDINE COMPOUNDS AND USE THEREOF FOR CONTROLLING HARMFUL FUNGI BASF AKTIENGESELLSCHAFT (DE) 2006-11-23 WO disclosed
EP-1417202-A2 AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY F. HOFFMANN-LA ROCHE AG (CH) 2004-05-12 EP disclosed
EP-1401826-A1 PYRAZOLE DERIVATIVES AS HIV REVERSE TRANSCRIPTASE INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2004-03-31 EP disclosed
US-20030069276-A1 Amino piperidine derivatives F.HOFFMANN-LA ROCHE AG (CH) 2003-04-10 US disclosed
US-6538015-B1 Process for their manufacture, pharmaceutical compositions and the use of such compounds in medicine. In particular, the compounds of formula I are inhibitors of the human immunodeficiency virus reverse transcriptase enzyme which is HOFFMANN-LA ROCHE INC. 2003-03-25 US disclosed
WO-2002100853-A1 PYRAZOLE DERIVATIVES AS HIV REVERSE TRANSCRIPTASE INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2002-12-19 WO disclosed
WO-2002079186-A2 AMINOPIPERIDINE DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY F. HOFFMANN-LA ROCHE AG (CH) 2002-10-10 WO disclosed