Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | AHCY | P23526 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PNP | P00491 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054167 | 1.00 | LMNA (0.58) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL2808298 | 1.00 | LMNA (0.58) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL3047081 | 0.90 | LMNA (0.50) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL25712959 | 0.88 | LMNA (0.59) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL3239663 | 0.88 | LMNA (0.59) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL7435133 | 0.87 | LMNA (0.58) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL4306006 | 0.87 | LMNA (0.55) | LMNANT5EHIF1AALDH1A1ALB | |
| SCHEMBL5548925 | 0.86 | LMNA (0.57) | LMNANT5EALDH1A1ALBMAPK1 | |
| SCHEMBL8124562 | 0.86 | LMNA (0.65) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL9601706 | 0.86 | LMNA (0.57) | LMNAALDH1A1ALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023178128-A1 | METHODS OF TREATING MEDICAL CONDITIONS USING ISLATRAVIR OR A RELATED COMPOUND | ROME THERAPEUTICS, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2021003129-A2 | ENGINEERED ACETATE KINASE VARIANT ENZYMES | CODEXIS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |
| WO-2021003132-A1 | ENGINEERED SUCROSE PHOSPHORYLASE VARIANT ENZYMES | CODEXIS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |