Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AHCY | P23526 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10438025 | 0.88 | ALDH1A1 (0.57) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL2808298 | 0.87 | LMNA (0.58) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL22862138 | 0.87 | LMNA (0.58) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL3054167 | 0.87 | LMNA (0.58) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL10379476 | 0.86 | ALDH1A1 (0.56) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL9601136 | 0.85 | LMNA (0.55) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL12154625 | 0.85 | ALDH1A1 (0.58) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| SCHEMBL9828081 | 0.81 | ALDH1A1 (0.58) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL29387997 | 0.81 | ALDH1A1 (0.61) | LMNAALDH1A1ALBMAPK1CYP1A2 | |
| Didanosine SCHEMBL1769151 | 0.81 | ALDH1A1 (0.61) | LMNAALDH1A1ALBMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009094577-A2 | MESOPHASIC FORMS OF (3S)-AMINOMETHYL-5-METHYL-HEXANOIC ACID PRODRUGS AND METHODS OF USE | XENOPORT, INC. (US) | 2009-07-30 | — | — | WO | disclosed |