Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490180 | 0.77 | AKT1 (0.39) | DPP4 | |
| SCHEMBL22862829 | 0.77 | AKT1 (0.39) | DPP4 | |
| SCHEMBL22862827 | 0.76 | CYP11B1 (0.40) | DPP4 | |
| SCHEMBL29490170 | 0.76 | CYP11B1 (0.40) | DPP4 | |
| SCHEMBL22862467 | 0.73 | HTT (0.43) | DPP4 | |
| SCHEMBL24704178 | 0.72 | HDAC1 (0.35) | RAD52MDM4TP53MDM2DPP4 | |
| SCHEMBL29490210 | 0.72 | POLB (0.49) | RAD52TP53 | |
| SCHEMBL22862547 | 0.72 | POLB (0.49) | RAD52TP53 | |
| SCHEMBL29490233 | 0.72 | HDAC1 (0.35) | RAD52MDM4TP53MDM2DPP4 | |
| SCHEMBL22862437 | 0.72 | CDK9 (0.40) | RAD52DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021002986-A2 | BAX INHIBITORS AND USES THEREOF | CASE WESTERN RESERVE UNIVERSITY (US) | 2021-01-07 | — | — | WO | disclosed |