Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 11/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17417754 | 0.86 | HSD17B10 (0.43) | NR4A2KDM4E | |
| SCHEMBL25425896 | 0.82 | NR4A2 (0.40) | NR4A2CREBBP | |
| SCHEMBL25748082 | 0.80 | NR4A2 (0.36) | NR4A2CREBBP | |
| SCHEMBL9937305 | 0.78 | NR4A2 (0.70) | NR4A2CREBBPMAP2K1 | |
| SCHEMBL18974967 | 0.77 | NR4A2 (0.35) | NR4A2 | |
| SCHEMBL25438497 | 0.77 | ALDH1A1 (0.39) | NR4A2 | |
| SCHEMBL25423189 | 0.77 | NR4A2 (0.34) | NR4A2 | |
| SCHEMBL17417650 | 0.76 | — | — | |
| SCHEMBL25423229 | 0.76 | NR4A2 (0.33) | NR4A2 | |
| SCHEMBL25436274 | 0.76 | ALDH1A1 (0.38) | NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021000935-A1 | HPK1 INHIBITORS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2021-01-07 | — | — | WO | disclosed |