SCHEMBL25423229

SCHEMBL25423229

COc1c(C)ccc2[nH]cc(C(=O)C(=O)N(C)C(C)C)c12

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ NR4A2 P43354 3/20 0.33
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ MITF O75030 1/20 0.32
▸ LMNA P02545 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25423189 0.89 NR4A2 (0.34) NR4A2MEN1KMT2AMITFLMNA
SCHEMBL25748082 0.87 NR4A2 (0.36) NR4A2MEN1KMT2AMITFLMNA
SCHEMBL25748171 0.85 ALDH1A1 (0.36) MEN1KMT2AALDH1A1CYP1A2CYP2C9
SCHEMBL25747864 0.83 HTR1A (0.35) NR4A2LMNAMAPTALDH1A1
SCHEMBL25436274 0.83 ALDH1A1 (0.38) NR4A2MEN1KMT2AMITFLMNA
SCHEMBL25748246 0.82 PTPN1 (0.38) MEN1KMT2AMAPTALDH1A1CYP2C9
SCHEMBL25438497 0.81 ALDH1A1 (0.39) NR4A2MEN1KMT2AMITFLMNA
SCHEMBL25422956 0.80 HTR1A (0.47) LMNAMAPTALDH1A1
SCHEMBL25425896 0.79 NR4A2 (0.40) NR4A2MEN1KMT2AMITFLMNA
SCHEMBL17417754 0.77 HSD17B10 (0.43) NR4A2MEN1KMT2AMITFLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250101038-A1 COMPOUNDS Psylo Pty Ltd (AU) 2025-03-27 — — US disclosed
EP-4452937-A1 COMPOUNDS Psylo Pty Ltd (AU) 2024-10-30 — — EP disclosed
CN-118715204-A Compounds of formula (I) 普赛洛私人有限公司 2024-09-27 — — CN disclosed
WO-2023115166-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed
WO-2023115166-A1 COMPOUNDS Psylo Pty Ltd (AU) 2023-06-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250101038-A1 COMPOUNDS NLN, SLC18A2, PYGB NR4A2 3254/4885MEN1 1401/4885KMT2A 2336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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