Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4EBP1 | Q13541 | 10/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ACP1 | P24666 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29560595 | 0.89 | EIF4EBP1 (0.39) | EIF4EBP1EGFRGPR35SORT1KDM4E | |
| SCHEMBL28715107 | 0.78 | GPR35 (0.45) | EIF4EBP1GPR35SORT1KDM4E | |
| SCHEMBL29560054 | 0.78 | KDM4E (0.39) | GPR35KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL22866725 | 0.78 | KDM4E (0.39) | GPR35KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL29559766 | 0.78 | EIF4EBP1 (0.37) | EIF4EBP1GPR35SORT1KDM4EALDH1A1 | |
| SCHEMBL22866908 | 0.78 | EIF4EBP1 (0.37) | EIF4EBP1GPR35SORT1KDM4EALDH1A1 | |
| SCHEMBL22866911 | 0.77 | CD38 (0.39) | GPR35KDM4EALDH1A1GAAHTT | |
| SCHEMBL22866471 | 0.73 | L3MBTL1 (0.34) | EIF4EBP1GPR35KDM4EL3MBTL1 | |
| SCHEMBL22866769 | 0.68 | TSHR (0.31) | EIF4EBP1GPR35 | |
| SCHEMBL22866921 | 0.65 | MAPT (0.33) | GPR35GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003157-A1 | EIF4E-INHIBITING 4-OXO-3,4-DIHYDROPYRIDO[3,4-D]PYRIMIDINE COMPOUNDS | EFFECTOR THERAPEUTICS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |