Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360901 | 0.83 | DRD2 (0.36) | DRD2DRD4DRD3SOS1 | |
| SCHEMBL25633371 | 0.80 | DRD2 (0.34) | DRD2DRD4DRD3SOS1 | |
| SCHEMBL12826444 | 0.77 | DRD2 (0.38) | DRD2DRD4DRD3SOS1 | |
| SCHEMBL20682229 | 0.74 | KDM4E (0.33) | DRD2DRD4DRD3SOS1 | |
| SCHEMBL14934068 | 0.74 | DRD2 (0.36) | DRD2DRD4DRD3 | |
| SCHEMBL25784871 | 0.73 | DRD2 (0.34) | DRD2DRD4DRD3 | |
| SCHEMBL25791832 | 0.71 | DRD2 (0.33) | DRD2DRD4DRD3 | |
| SCHEMBL19163915 | 0.70 | DRD2 (0.30) | DRD2DRD4DRD3 | |
| SCHEMBL26311187 | 0.69 | KCNA5 (0.32) | DRD2DRD4DRD3 | |
| SCHEMBL25682197 | 0.66 | DRD2 (0.35) | DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542275-B2 | Substituted imidazolidin-2-one derivatives as PRMT5 inhibitors | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2023-01-03 | — | — | US | disclosed |
| US-20210002298-A1 | SUBSTITUTED IMIDAZOLIDIN-2-ONE DERIVATIVES AS PRMT5 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2021-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542275-B2 | Substituted imidazolidin-2-one derivatives as PRMT5 inhibitors | PRMT5, PRMT1, PRMT8 | DRD2 4655/4885DRD4 4410/4885DRD3 4559/4885 |
| US-20210002298-A1 | SUBSTITUTED IMIDAZOLIDIN-2-ONE DERIVATIVES AS PRMT5 INHIBITORS | PRMT5, PRMT1, PRMT8 | DRD2 4655/4885DRD4 4410/4885DRD3 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.