Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12826444 | 0.83 | DRD2 (0.38) | DRD2DRD3DRD4HRH3 | |
| SCHEMBL10360901 | 0.79 | DRD2 (0.36) | DRD2DRD3DRD4LMNAHRH3 | |
| SCHEMBL25633371 | 0.76 | DRD2 (0.34) | DRD2DRD3DRD4 | |
| SCHEMBL14912863 | 0.74 | ADORA2A (0.33) | DRD2HTR2AHRH1LMNAHRH3 | |
| SCHEMBL22867309 | 0.74 | DRD2 (0.33) | DRD2DRD3DRD4 | |
| SCHEMBL17147100 | 0.73 | ACHE (0.35) | DRD2DRD3DRD4KMT2ALMNA | |
| SCHEMBL17656168 | 0.71 | BTK (0.32) | DRD2HTR2AHRH1LMNA | |
| SCHEMBL20682229 | 0.71 | KDM4E (0.33) | DRD2DRD3DRD4LMNAHRH3 | |
| SCHEMBL25784871 | 0.70 | DRD2 (0.34) | DRD2DRD3DRD4 | |
| SCHEMBL14912660 | 0.70 | ALDH1A1 (0.32) | DRD2HTR2AHRH1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013067274-A1 | HETEROARYL PYRIDONE AND AZA-PYRIDONE COMPOUNDS AS INHIBITORS OF BTK ACTIVITY | GENENTECH, INC. (US) | 2013-05-10 | — | — | WO | disclosed |